Comprehensive neurocognitive
risk assessments

Assess your risk for Alzheimer's, Parkinson's, vascular dementia, and more.

Comprehensive tests to identify Alzheimer's disease

Using various assessments, Florence analyzes your vascular health to help you understand your risk of various neurocognitive disorders.

Retinal images serve as a "window" into your broader health, offering insights into systemic diseases.

Retinal Imaging

Retinal images serve as a "window" into your broader health, offering insights into systemic diseases and overall health.

Phosphorolated Tau-217

Used to assess Alzheimer's disease risk by measuring phosphorylated tau 217, a surrogate of amyloid pathology.

A quick retinal image is all it takes to uncover potential brain health risks.

APOE Genotyping

Detects the presence of the APOE4 variant, which is associated with risk of late-onset Alzheimer's disease.

Clinical Evaluation

A clinical evaluation with a cognitive health specialist.


Actionability

Clinically actionable next steps to help reduce risk of neurocognitive disorders.


Track Changes Over Time

Track changes in your cognitive risk profile with regular follow-up assessments and updates.

"Modifying 14 risk factors might prevent or delay nearly half of dementia cases"

"Modifying 14 risk factors might prevent or delay nearly half of dementia cases"

Lancet, 2024

Lancet, 2024

Florence provides a non-invasive way to tell if you are at risk. Take the steps to improve your brain health.

Florence provides a non-invasive way to tell if you are at risk. Take the steps to improve your brain health.

How it works

First

Connect with partner clinic

After completing an intake form, we will connect you with one of our partner clinics. If we do not have a partner clinic in your area, we will work with a local provider.

Second

Complete retinal scan

Our partner clinic will do Color Fundus Photography (CFP) and Optical Coherence Tomography with Angiography (OCT-A) scans of your retina.

Third

Blood tests and saliva sample

We will send a phlebotomist to your home for a blood draw. At this time, we will also collect the saliva sample.

Fourth

Receive results

We analyze the images and generate a report for you and your physician.

Science

Backed by clinically-validated research

The underlying science behind Florence’s technology is rooted in retinal imaging and advanced machine learning. By analyzing extensive data from Color Fundus Photography (CFP) and Optical Coherence Tomography (OCT) images, machine learning algorithms learn to recognize subtle retinal patterns linked to a variety of diseases.

Retinal images serve as a "window" into broader health, offering insights into the risks of systemic diseases such as Parkinson's and Alzheimer's Disease, heart disease, and stroke risk.

The Vision

We believe in a future where simple screening modalities, such as retinal exams, can provide vast, high-quality, actionable information regarding a patient's health.